University of California San Diego - Literature
Postdoctoral Scholar in Prof. Gerard Wong's group, Department of Bioengineering, UCLA
Biotechnology
Yue
Zhang
San Diego, California
A self-motivated formulation scientist with 5+ years of research experience in the academic and industrial setting.
1. Extensive background in Chemistry and Material Science.
2. Successful bench scientist with strong scholastic achievement and publication records.
3. Good practice in chemical modification of hydrophilic polymers.
4. Extensive experience in developing and characterizing drug-loaded nanoparticle formulation.
5. A fast learner with proven teamwork and multi-tasking ability when managing projects and experiments.
6. Excellent communication (written and oral) and interpersonal skill developed by leading UCSD Chinese student association for 3 years.
Please feel free to visit the full list of my publications here:
https://scholar.google.com/citations?user=q348IHYAAAAJ&hl=en
Undergraduate Research Assistant in Dr. Zhiping Zhang's lab
Summary: Characterize and quantify active pharmaceutical ingredient in the nanoparticle formulation
1. Received extensive training of drug delivery methodology and nanomedicine development.
2. Analyzed and determined and drug release kinetics from polymeric nanoparticles.
Postdoctoral Scholar
Y worked at University of California, Los Angeles as a Postdoctoral Scholar
President
The association aimed to facilitate the adaptation of Chinese students to life/study in the US.
1. Led a team of 4 graduate students and engaged in the planning of social events for each year. Successfully organized 3 events with ~100 attendees each and secured $1000+ funding from Chinese Consulate-General in Los Angeles.
2. Managed 3 online chatting rooms of 500+ members each. Advised new students or visiting scholars on the topics of on/off-campus housing, local transportation, insurance, career development, etc. Effectively communicated the common issues with Chinese Consulate-General in Los Angeles.
3. Awarded the 2016 Best Chinese Student Association by Chinese Consulate-General in Los Angeles.
Graduate Student Researcher
Summary: Engineer structurally hierarchical nanomaterials for biological threats removal.
1. One-dimensional platform: Red blood cell membrane-coated nanogel (RBC-nanogel) for redox-responsive antimicrobial delivery against intracellular Staphylococcus aureus infection.
2. Two-dimensional platform: A bio-adhesive nanoparticle-hydrogel hybrid system for localized antibiotic delivery.
3. Three-dimensional platform: Self-assembled RBC colloidal gel for anti-virulence treatment in group A streptococcus (GAS) soft tissue infection.
4. Finished 2 external collaboration projects to expand the application of the new drug formulation.
5. 14 publications in high-impact journals. (Nature Nanotech, J. Control. Release, Adv Mater, ACS Nano, etc.)
6. Trained 7 undergraduates on formulation synthesis and basic laboratory skills.
Spring Intern in Dr. Moritz Bünemann lab
Summary: Visualize real-time β-Arrestin and ARF-6 interaction in single cell with fluorescence resonance energy transfer (FRET)-mediated imaging system.
1. Designed and constructed plasmids encoding YFP labelled β-Arrestin and GFP labelled ARF-6. The intracellular location of β-Arrestin /ARF-6 was controlled by inserting a short lipopholic domain when constructing the plasmid. The plasmids were further amplified, purified and transfected into HEK293T cells.
2. Studied the real-time β-Arrestin and ARF-6 interaction in HEK293T cell when β-Arrestin were stimulated with isoproterenol. To visualize the signaling process, the degree of FRET was measured by confocal fluorescence microscopy and normalized based on emission spectrum overlap to evaluate the proximity of two FRET pair labelled proteins.
Bachelor of Science - BS
Pharmacy
Undergraduate Research Assistant in Dr. Zhiping Zhang's lab
Summary: Characterize and quantify active pharmaceutical ingredient in the nanoparticle formulation
1. Received extensive training of drug delivery methodology and nanomedicine development.
2. Analyzed and determined and drug release kinetics from polymeric nanoparticles.
Doctor of Philosophy (PhD)
Pharmaceutical Sciences
Graduate Student Researcher
Summary: Engineer structurally hierarchical nanomaterials for biological threats removal.
1. One-dimensional platform: Red blood cell membrane-coated nanogel (RBC-nanogel) for redox-responsive antimicrobial delivery against intracellular Staphylococcus aureus infection.
2. Two-dimensional platform: A bio-adhesive nanoparticle-hydrogel hybrid system for localized antibiotic delivery.
3. Three-dimensional platform: Self-assembled RBC colloidal gel for anti-virulence treatment in group A streptococcus (GAS) soft tissue infection.
4. Finished 2 external collaboration projects to expand the application of the new drug formulation.
5. 14 publications in high-impact journals. (Nature Nanotech, J. Control. Release, Adv Mater, ACS Nano, etc.)
6. Trained 7 undergraduates on formulation synthesis and basic laboratory skills.
The following profiles may or may not be the same professor:
The following profiles may or may not be the same professor: