Resume

• 2011

  Seton Hall University

  Teaching Biology-related subjects in the Biology department: Anatomy and Physiology (+lab)

  Biology

  Neuroendocrinology

  Senior Seminars in Biology

  Seton Hall University

• 2004

  Lundbeck Research USA

  NJ

  Teaching Anatomy and Physiology with Lab

  Adjunct Professor

  Bergen Community College

  Supported early target identification and validation for anxiety/depression and mood disorders:\na. Contributed to the identification and evaluation of new drug development opportunities for mood disorders.\nb. Target champion for early project on neuroplasticity target\nc. Established neuro-plasticity platform for target evaluation and mechanistic studies

  including: \n - in vitro cell-based assays and cellular models of neuroplasticity (HCS neurite outgrowth) and neuroinflammation\n - siRNA-mediated gene knock down in primary neurons\n - gene expression analysis and biochemical readouts\nd. Supervised senior associate researcher and coached scientist\ne. Established and maintained collaborations with academic labs and CROs\nf. Coordinated development of in vivo delivery of shRNA via viral vectors with molecular and in vivo biologists

  resulting in project advancement to generate tool compounds

  Lundbeck Research USA

• 2000

  Biogen Idec

  Supported target validation for spinal cord injury (biologics):\na. developed in vitro cellular assays as models for spinal cord axonal regeneration using high content screening (HCS) on primary neurons and neuronal cell lines\nb. evaluated drug opportunities for neurodegeneration using neuronal primary cultures\nc. identified and managed external collaboration with academic laboratoris to advance project on spinal cord regeneration \nd. organized internal symposium with invited speakers from academia

  Biogen Idec

• 1997

  Columbia University Medical School

  - Mechanisms of neuronal death induced by trophic factor deprivation and oxidative stress on PC12 cells and primary neuronal cultures. \n- Identified critical role of caspase 2 in beta-amyloid induced cell death

  as cellular model of Alzheimer's disease. \n(Prof. Carol Troy)

  Columbia University Medical School

• 1994

  Medical College of Pennsylvania (Drexel U)

  a. in vitro cellular studies of neurotrophins and repulsive molecules (Semaphorins) in the developing cerebellar system. \nb. supervised a graduate student and an undergraduate student. (Prof. D Baird)

  Medical College of Pennsylvania (Drexel U)

• 1991

  Scuola Normale Superiore and CNR (Pisa)

  Development and plasticity in the mammalian visual system.\na. cellular and molecular studies of developmental plasticity in the rat visual system. \nb. in vivo investigation of the mechanisms of degeneration (apoptosis) of axotomized retinal ganglion cells in neonatal rats and bcl2-overexpressing mice. \nc. supervising two PhD students and undergraduate students. \nd. awarded research grants from the \"International Institute of Paraplegia\"

  Switzerland.

  Scuola Normale Superiore and CNR (Pisa)

• 1989

  Universite P et M Curie

  Paris

  France

  Neuronal plasticity in developing and adult cerebellar system.\na. in vivo intracellular recordings in developing cerebellum of chimeric and mutant mice and of rats after chronic treatment with NMDA agonist/antagonist

  to study the mechanisms of synapse elimination/stabilization. \nb. awarded fellowship grants from Fondation Fyssen and from Fondation IPSEN

  Universite P et M Curie

  Paris

  France

• 1986

  Italian

  PhD

  Thesis work performed at Harvard Medical School

  dept of Neurobiology (Prof U. Drager):\n\" A positional marker for the dorsal retina is homologous to the high affinity laminin receptor\"

  Neuroscience

  Università degli Studi di Torino

• 1980

  Laurea

  Thesis: at Dept of Neurophysiology

  Medical School

  Universita di Torino

  (Prof P Strata's lab):\n\"Plasticity phenomena in the olivo-cerebellar system\"

  Biological Sciences

• Biology

  Western Blotting

  Lifesciences

  High Content Screening

  In Vivo

  Neuroscience

  Physiology

  Immunohistochemistry

  Biochemistry

  Drug Discovery

  Cell Culture

  CRO

  In Vitro

  Molecular Biology

  Cell Biology

  Neuroanatomy

  Cell

  Rabacchi

  Sylvia

  Rabacchi

  Bergen Community College