Resume

• 908286

  Certificate of Eligibility

  Teacher of Mathematics

  State of New Jersey

• 2002

  PhD

  Biomedical Engineering

  Introduction to Colloid and Surface Chemistry

  Nano and Micro Bio-Interfaces

  Biopolymers

• 1992

  BS

  Mechanical Engineering

  Tau Beta Pi

  National Engineering Honor Scociety\nPi Tau Sigma

  Mechanical Engineering Honor Society

• Quartz Crystal Microbalance

  Spectrophotometry

  Infrared Spectrosocpy (FTIR)

  Differential Scanning Calorimetry

  Ellipsometry

  Surface Chemistry

  TGA

  ELISA

  Microfluidics

  UV absorbance

  Matlab

  PCR

  Fluorescence Microscopy

  Fluorescence

  RNA extraction

  Characterization

  qPCR

  UV-Vis

  DNA extraction

  Sample Preparation

  Attachment of Streptavidin-Biotin on 3–Aminopropyltriethoxysilane (APTES) Modified Porous Silicon Surfaces

  Yves J. Chabal

  ORDER OF AUTHORSHIP: Shalini Singh

  Norman Lapin

  Yves J. Chabal

  Attachment of Streptavidin-Biotin on 3–Aminopropyltriethoxysilane (APTES) Modified Porous Silicon Surfaces

  Stuart Corr

  Steven Curley

  Intravital microscopy for evaluating tumor perfusion of nanoparticles exposed to non-invasive radiofrequency electric fields

  David I. Shreiber

  Jennifer R. Miksan

  Yves J. Chabal

  Harini Sundararaghavan

  ORDER OF AUTHORSHIP: Sundararaghavan HG

  Monteiro G

  Lapin NA

  Chabal YJ

  Jennifer R. Miksan

  and David I. Shreiber

  Genipin-induced changes in collagen gels: Correlation of mechanical properties to fluorescence

  Yves J. Chabal

  Infrared Characterization of Biotinylated Silicon Oxide Surfaces

  Surface Stability

  and Specific Attachment of Streptavidin

  Steven Curley

  Lon Wilson

  Sean Dilliard

  The effects of non-invasive radiofrequency electric field hyperthermia on biotransport and biodistribution of fluorescent [60] fullerene derivative in a murine orthotopic model of breast adenocarcinoma

  Rita Serda

  Steven Curley

  Lon Wilson

  Sean Dilliard

  Biotransport kinetics and intratumoral biodistribution of malonodiserinolamide-derivatized [60]fullerene in a murine model of breast adenocarcinoma

  Yves J. Chabal

  Chapter 4. Infrared Analysis of Biomolecule Attachment to Functionalized Silicon Surfaces.

  Biointerface characterization by advanced IR spectroscopy: Chapter 4

  Highly skilled and ingenuitive biomedical scientist/engineer with extensive experience in biomedical imaging

  image processing and analysis and small animal handling. Proficient in multiple MRI imaging modalities and confocal & multiphoton microscopy applied to mouse models in cancer and neuropathology. Adept at vitals monitoring and imaging of live anesthetized mice. Skilled in drug and nanoparticle delivery via tail vein cannulation. Creative

  resourceful and thorough designer of experiments. Highly effective and engaging teacher and conference presenter. Proficient in Mandarin Chinese

  written and spoken.

  Norman

  Lapin

  WyzAnt Tutoring

  Beijing Polytechnic University

  Rutgers University

  Touro College

  Visteon Corporation

  Biosample Solutions

  LLC

  Sandia National Laboratories

  Baylor College of Medicine

  Salvona Technologies

  Allen Park

  MI

  Designed and built prototypes of modules for vehicle dashboard\nConducted vibration and temperature testing of dashboard modules\nWorked with manufacturers in China & Brazil on assembly and scale up\nSpoke Chinese with manufacturers and suppliers in Shanghai

  China\nLed/Collaborated on multidisciplinary product teams (mechanical and electrical designers

  plastics suppliers and artistic design group)

  Product Design Engineer

  Visteon Corporation

  Houston

  Texas Area

  Magnetic Resonance Imaging\n* Anatomical imaging of longitudinal brain tumor growth

  liver

  kidneys

  heart

  aorta * Cardiac Imaging * Delayed Contrast Enhancement quantification of contrast agent * T1/T2 Mapping to quantify tissue * Diffusion Weighted Imaging (study on Cortical Spreading Depression) * Diffusion Tensor Imaging of structural brain * Resting State functional MRI for analysis of brain functional networks (one of only a few groups able to perform this technique on mice)\n\nAnimal Work\n* Precise monitoring and modulation of heart rate

  respiration and body temperature while imaging\n* Expertise in intranasal delivery of nanotherapeutic to brain in mice to treat neurodegenerative disease\n* Experienced in mouse and rat tail-vein cannulation with IV drug and nanoparticle delivery\n\nExperience with disease models in mice\n* APP (Alzheimer’s Disease) and MDX (Duchenne Muscular Dystrophy)\n* Behavioral studies including Open Field

  Conditioned Fear and Rotarod assays\n\nImage analysis\n* Utilized ImageJ for Western blot quantification and measurements of anatomical structures\n* Applied Matlab to automate segmentation of Diffusion Tensor Imaging (DTI) brain structures \n* Integrated Matlab

  MRI Studio and TrackVis software to create segmented mouse brain tractography with axon bundle fiber tracking specific to individual brain regions\n\nTissue processing\n* Expertise in Western blot preparation and analysis of brain tissue\n* Proficient in extraction

  dissection

  identification and isolation of brain structures\n* Experience in paraffin embedding

  snap cryofreezing and immunohistochemistry\n\nTeaching and Leadership\n* Mentored SMART Program undergraduate student on resting state functional MRI\n\nRelevant Software\nMATLAB\nImageJ (image processing and quantification)\nOsirix (medical imaging and quantification)\nMRI Studio (diffusion tensor imaging)\nTrackVis (tractography of fibers in the brain)\nAMIRA (3-D rendering)\nPrism (statistical analysis)

  Research Associate

  Baylor College of Medicine

  Brooklyn

  Manhattan & Queens

  NY

  Courses taught\t\n•\tBIO-530: Biotechnology (Honors) Lecture\n•\tBIO-228: Microbiology Laboratory\n•\tBIO-211: Molecular Genetics Laboratory\n•\tGSB-101 Biology I: Lecture & Laboratory\n•\tGSB-102 Biology II: Lecture & Laboratory \n•\tBIO-111: Human Biology for Non-Majors

  Adjunct Instructor

  Touro College

  Piscataway

  NJ

  Course: Biomechanics\nCourse: Biomedical Transport Phenomena\nLaboratory Instructor: Authored and instructed biomedical engineering labs

  Teaching Assistant

  Rutgers University

  Dayton

  New Jersey

  •\tDeveloped & formulated over 20 products for controlled delivery & release in skincare

  cosmetic & OTC pharmaceutical (oral & topical) applications in cooperation with research and applications teams.\n•\tInstructed sales & marketing team in proprietary technology for customer interaction & brand strategizing.\n•\t Communicated with sales and marketing teams to clarify proprietary technologies for interaction with customers and brand strategizing\n\nRelevant Skills\nParticle Distribution Analysis\nMicroscopy (examination/identification of materials)\nViscometry (materials characterization)\nDifferential Scanning Calorimetry (DSC)\nThermogravimetric Analysis (TGA)\npH measurement\nHigh-performance liquid chromatography (HPLC)\nOperation of industrial homogenizers

  mixers and grinders

  Product Engineer

  Salvona Technologies

  Albuquerque

  New Mexico Area

  Project: Surface acoustic wave streaming removal of protein on microarray surfaces\nDemonstrated removal of protein using surface acoustic waves in microfluidic chamber with real-time imaging of decrease in fluorescently-label protein\n•\tPerformed microarray photoresist patterning and fluorescence labeling of antibodies\n•\tConducted electrical characterization and bench testing of acoustic devices\n•\tSetup fixtures/ Ran microfluidics\n•\tConducted in-situ microfluidic fluorescence microscopy\n•\tAssisted with robotic protein array spotting

  Intern

  Microsensor Science and Technology Department

  Sandia National Laboratories

  Undergraduate Senior Design Project:\nUtilized artificial neural network and force transducers to train computer to detect abnormal machining vibration

  Beijing Polytechnic University

  Biosample Solutions

  LLC

  Bethlehem

  PA

  •\tDesigned and developed formulations

  protocols and procedures for cell lysis and nucleic acid extraction from blood/saliva and DNA capture on silica matrices with elution for diagnostics applications\n•\tConducted Labview-automated pipette anti-contamination studies\n•\tConducted nucleic acid stability studies\n•\tRan pilot production of extraction kits with QC validation using PCR

  qPCR

  Nanodrop

  UV-Vis absorbance

  Tecan fluorescence microplate reader\n•\tRapidly trained new employees in these techniques and methods\n•\tTrained new employees in above processes and methods\n\nRelevant Skills\nPCR\nqPCR (Biorad iQ)\nUV-Vis spectroscopy\nNanodrop (UV Absorbance)\nTecan fluorescence microplate reader\nLabview-automated pipette\nDBS (Dried Blood Spot storage) \nELISA

  Research Scientist

  Piscataway

  NJ

  Thesis work\n•\tIdentified new infrared signatures of surface-bound biotin-streptavidin and antibody attachment systems through advanced Fourier Transform Infrared spectroscopy (FTIR)\n•\tModified surface biochemistry and monitored layer by layer attachment at inorganic surfaces

  quantifying adsorption of chemical & protein layers through FTIR

  Ellipsometry & Fluorescence Microscopy\n\nCollaboration\n•\tCharacterized and quantified in-situ collagen crosslinking using multiple internal reflection FTIR as part of project to tune mechanical stiffness gradient in collagen scaffolds for nerve regrowth

  Graduate Assistant

  Rutgers University

  Houston

  Texas

  Intravital Microscopy (IVM) of surgically exposed breast cancer tumors in live anesthetized mice \n* Real-time intravenous delivery of various drugs and nanoparticles including doxorubicin

  quantum dots and fullerenes to tumor site. Mouse cancer models: Orthotopic & ectopic 4T1 breast tumor in Balb/c mice\n* IVM with adjuvant in situ radiofrequency-induced hyperthermia treatment\nNanoparticle Characterization: Dynamic Light Scattering & Zeta Potential measurements (Malvern Zetasizer)\nMentored SMART Program undergraduate student on binary thresholding analysis of intravital microscopy data and coached him on presentation of data to his cohort\nCell Culture Experience: Cell splitting

  counting with cell counter and injection in mice for tumor growth\n\nKey Skillset\nConfocal/multiphoton microscopy

  fluorescence and brightfield microscopy. Mouse anesthesia and surgical techniques

  retro-orbital injection & tail vein cannulation. IVM software: NIS-Elements.

  Postdoctoral Associate

  Department of Surgery

  Division of Surgical Research

  Baylor College of Medicine

  Brooklyn

  NY

  Instruction in elementary to college level mathematics and science\nConsulting on research papers and projects

  Tutor / Consultant

  WyzAnt Tutoring

  Chinese

  Spanish

  Graduate Fellow

  NIH Rutgers/UMDNJ Biotechnology Training Program

  2005 – 2008

  Rutgers University

  Best Poster Award

  FTIR investigation of the attachment between aminosilane

  biotin and streptavidin

  21st Annual Symposium of the Laboratory for Surface Modification

  Graduate Fellow

  Graduate Assistance in Areas of National Need (GAANN)

  2004 – 2005

  Rutgers University