Mac Robinson

 MacB. Robinson

Mac B. Robinson

  • Courses2
  • Reviews3

Biography

Guilford Technical Community College - Biology


Resume

  • 2010

    Master’s Degree

    Clinical and Population Translational Sciences

    Investigation of SNPs within the corticosteroid pathway and association with lung function

    steroid use and healthcare utilization in individuals with asthma.

    Wake Forest University

  • 2001

    PhD

    Molecular Genetics/Neurobiology and Anatomy

    In my project I was undertaking a biotherapeutic approach in efforts to mitigate developmental and stress induced cell death in motoneurons. I cloned the Hsc70 sequence and developed methods to generated the full length protein and protein fragments and mutants for use in vitro and in vivo. I was also involved in its use in a mouse model of amyotrophic lateral sclerosis (ALS). Later

    I was responsible for a project to search for novel biomarkers in ALS.

    Wake Forest University School of Medicine

  • 1994

    BS

    Biology

  • Cell Culture

    Animal Models

    Molecular Biology

    Western Blotting

    Immunohistochemistry

    Robinson

    Wake Forest School of Medicine

    UNC Lineberger Comprehensive Cancer Center

    Wake Forest University

    Wake Forest Baptist Health

    Guilford Technical Community College

    Elucidation of disease specific biomarkers in ALS\nInvestigation of the motoneuron response to stress.\n\nMechanisms of the motoneuron stress response

    Wake Forest University

    Clinical Protocol and Grant Writer

    Wake Forest Baptist Health

    Wake Forest University

    Center for Genomics

    We are working to determine the mechanisms associated with the multimerization status of adiponectin in relation to the genotype of individuals with diabetes.

    Research Fellow

    Wake Forest School of Medicine

    Clinical Protocol Development Associate

    UNC Lineberger Comprehensive Cancer Center

    Adjunct Instructor

    Teach Anatomy and Physiology Lecture and Laboratories.

    Guilford Technical Community College

    Wake Forest University

    Wake Forest University/Center for Genomics and Personalized Medicine Research

    My projects include a number of different approaches to examine the pathological influences of the IL6 inflammatory pathway in asthma. Additionally

    one my interests is the contribution of molecular chaperones to disease. In particular

    we are examining how chaperones affect the corticosteroid pathway. \n1) We determine the functional implications of IL6 and IL6 transsignaling in airway smooth muscle and how it may play a role in the pathophysiology of asthma and other obstructive pulmonary diseases. \n\n2) Also

    we investigate alterations in soluble IL6 receptor in various population of individuals with asthma and chronic obstuctive pulmonary disease. \n\n3) Finally

    we are also investigating genetic mutations within the steroid pathway to determine potential association with lung function

    steroid use and healthcare utilization.

    Research Fellow/K12 Scholar

    Winston Salem

    NC

    Principal Investigator/Study Director: \nTest products for the treatment of cutaneous radiation injury. Provide project management

    data management

    interim statistical analyses

    and study reporting responsibilities.\n\nCo-Investigator:\nDevelop and test recombinant protein biotherapeutics and derivatives for use and treatment in a model of amyotrophic lateral sclerosis (Lou Gehrig's Disease). Characterize the molecular and physiological targets of the biotherapeutic.\n\nExamine inflammatory pathways contributing to ALS pathology.\n\nInvestigate gene expression in skeletal muscle to uncover expression markers associated with various parameters of ALS pathology.\n\nTeach graduate level Cell Death Lectures.

    Instructor

    Wake Forest University

BIO 165

4.8(2)

BIOLAB 165

4(1)