John B. Rudell
- Courses2
- Reviews11
- School: Napa Valley College
- Campus:
- Department: Biology
- Email address: Join to see
- Phone: Join to see
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Location:
2277 Napa-Vallejo Highway
Napa, CA - 94558 - Dates at Napa Valley College: January 2013 - August 2017
- Office Hours: Join to see
Biography
Napa Valley College - Biology
Experience
Napa Valley College
Adjunct Professor
John worked at Napa Valley College as a Adjunct Professor
Education
University of California, Davis
Bachelor's degree
Wildlife, Fisheries and Conservation Biology
University of California, Davis
Doctor of Philosophy (Ph.D.)
Cellular, Molecular and Integrative Physiology
Utilized chimeric protein expression, co-immunoprecipitation, immunoblot, immunocytochemistry and pulse-chase techniques to determine the role of phosphorylation and protein-protein interactions in acetylcholine receptor (AChR) localization and stabilization at the neuromuscular junction. • Maintained two separate transgenic mouse colonies, genotyped mice, constructed chimeras in expression plasmids. • Dissected and cultured superior cervical ganglia neurons, maintained multiple immortal cell lines, transfected/infected cultured autonomic neurons as well as myoblasts and heterologous cells with expression plasmids, created stably transfected cell lines. • Immunostained cultures, and performed AChR turnover studies using radioactive I125 alpha-bungarotoxin. • Obtained and analyzed immunocytochemical, immunoblot and radioactive data.University of California, Davis
Master's degree
Nutritional Neuroscience
Investigated the role of the anterior piriform cortex (APC) in the detection of an indispensable amino acid deficient diet by direct in vivo application of pharmacological reagents to the rat APC as well as in vitro slice electrophysiology. • Used stereotaxic surgery in the rat brain, performed in vivo experiments using instrumented rats, prepared diets, performed food intake and behavioral measurements, verified cannula placement using histology and performed statistical data analysis. • Demonstrated that the APC is capable of detecting an indispensable amino acid deficiency independent of other neural inputs via in vitro slice electrophysiology. Performed proof of concept experiments to show that the in vitro slice model was useful for these studies. • Performed dissection of rat APC, prepared electrophysiological solutions, maintained electrophysiology equipment, and recorded and analyzed electrophysiological data from brain slices. • Performed statistical analysis of data.
Publications
Uncharged tRNA and sensing of amino acid deficiency in mammalian piriform cortex
Science
Uncharged tRNA and sensing of amino acid deficiency in mammalian piriform cortex
Science
Determinants in the beta and delta subunit loop regulate golgi trafficking and surface expression of the muscle acetylcholine receptor
The Journal of Biological Chemistry
Uncharged tRNA and sensing of amino acid deficiency in mammalian piriform cortex
Science
Determinants in the beta and delta subunit loop regulate golgi trafficking and surface expression of the muscle acetylcholine receptor
The Journal of Biological Chemistry
The anterior piriform cortex is sufficient for detecting depletion of an indispensable amino acid, showing independent cortical sensory function
The Journal of Neuroscience
Uncharged tRNA and sensing of amino acid deficiency in mammalian piriform cortex
Science
Determinants in the beta and delta subunit loop regulate golgi trafficking and surface expression of the muscle acetylcholine receptor
The Journal of Biological Chemistry
The anterior piriform cortex is sufficient for detecting depletion of an indispensable amino acid, showing independent cortical sensory function
The Journal of Neuroscience
Rapsyn interacts with the muscle acetylcholine receptor via alpha-helical domains in the alpha, beta and epsilon subunit intracellular loops
Neuroscience
Uncharged tRNA and sensing of amino acid deficiency in mammalian piriform cortex
Science
Determinants in the beta and delta subunit loop regulate golgi trafficking and surface expression of the muscle acetylcholine receptor
The Journal of Biological Chemistry
The anterior piriform cortex is sufficient for detecting depletion of an indispensable amino acid, showing independent cortical sensory function
The Journal of Neuroscience
Rapsyn interacts with the muscle acetylcholine receptor via alpha-helical domains in the alpha, beta and epsilon subunit intracellular loops
Neuroscience
Rapsyn carboxyl terminal domains mediate muscle specific kinase-induced phosphorylation of the muscle acetylcholine receptor
Neuroscience
Uncharged tRNA and sensing of amino acid deficiency in mammalian piriform cortex
Science
Determinants in the beta and delta subunit loop regulate golgi trafficking and surface expression of the muscle acetylcholine receptor
The Journal of Biological Chemistry
The anterior piriform cortex is sufficient for detecting depletion of an indispensable amino acid, showing independent cortical sensory function
The Journal of Neuroscience
Rapsyn interacts with the muscle acetylcholine receptor via alpha-helical domains in the alpha, beta and epsilon subunit intracellular loops
Neuroscience
Rapsyn carboxyl terminal domains mediate muscle specific kinase-induced phosphorylation of the muscle acetylcholine receptor
Neuroscience
Identification of a motif in the acetylcholine receptor beta subunit whose phosphorylation regulates rapsyn association and postsynaptic receptor localization
The Journal of Neuroscience
Uncharged tRNA and sensing of amino acid deficiency in mammalian piriform cortex
Science
Determinants in the beta and delta subunit loop regulate golgi trafficking and surface expression of the muscle acetylcholine receptor
The Journal of Biological Chemistry
The anterior piriform cortex is sufficient for detecting depletion of an indispensable amino acid, showing independent cortical sensory function
The Journal of Neuroscience
Rapsyn interacts with the muscle acetylcholine receptor via alpha-helical domains in the alpha, beta and epsilon subunit intracellular loops
Neuroscience
Rapsyn carboxyl terminal domains mediate muscle specific kinase-induced phosphorylation of the muscle acetylcholine receptor
Neuroscience
Identification of a motif in the acetylcholine receptor beta subunit whose phosphorylation regulates rapsyn association and postsynaptic receptor localization
The Journal of Neuroscience
Regulation of muscle acetylcholine receptor turnover by beta subunit tyrosine phosphorylation
Developmental Neurobiology
Uncharged tRNA and sensing of amino acid deficiency in mammalian piriform cortex
Science
Determinants in the beta and delta subunit loop regulate golgi trafficking and surface expression of the muscle acetylcholine receptor
The Journal of Biological Chemistry
The anterior piriform cortex is sufficient for detecting depletion of an indispensable amino acid, showing independent cortical sensory function
The Journal of Neuroscience
Rapsyn interacts with the muscle acetylcholine receptor via alpha-helical domains in the alpha, beta and epsilon subunit intracellular loops
Neuroscience
Rapsyn carboxyl terminal domains mediate muscle specific kinase-induced phosphorylation of the muscle acetylcholine receptor
Neuroscience
Identification of a motif in the acetylcholine receptor beta subunit whose phosphorylation regulates rapsyn association and postsynaptic receptor localization
The Journal of Neuroscience
Regulation of muscle acetylcholine receptor turnover by beta subunit tyrosine phosphorylation
Developmental Neurobiology
Effects of essential amino acid deficiency: down-regulation of KCC2 and the GABAa receptor; disinhibition in the anterior piriform cortex
The Journal of Neurochemistry
Uncharged tRNA and sensing of amino acid deficiency in mammalian piriform cortex
Science
Determinants in the beta and delta subunit loop regulate golgi trafficking and surface expression of the muscle acetylcholine receptor
The Journal of Biological Chemistry
The anterior piriform cortex is sufficient for detecting depletion of an indispensable amino acid, showing independent cortical sensory function
The Journal of Neuroscience
Rapsyn interacts with the muscle acetylcholine receptor via alpha-helical domains in the alpha, beta and epsilon subunit intracellular loops
Neuroscience
Rapsyn carboxyl terminal domains mediate muscle specific kinase-induced phosphorylation of the muscle acetylcholine receptor
Neuroscience
Identification of a motif in the acetylcholine receptor beta subunit whose phosphorylation regulates rapsyn association and postsynaptic receptor localization
The Journal of Neuroscience
Regulation of muscle acetylcholine receptor turnover by beta subunit tyrosine phosphorylation
Developmental Neurobiology
Effects of essential amino acid deficiency: down-regulation of KCC2 and the GABAa receptor; disinhibition in the anterior piriform cortex
The Journal of Neurochemistry
Co-localization of phosphorylated extracellular signal-regulated protein kinases 1/2 (ERK1/2) and phosphorylated eukaryotic initiation factor 2alpha (eIF2alpha) in response to a threonine-devoid diet
The Journal of Comparative Neurology
