Henry Young

  1. Home
  2. Georgia
  3. Mercer University
  4. Henry Young
HenryE. Young

Henry E. Young

  • Courses1
  • Reviews1
Rate This Professor

Social Profile:

Join to see

Biography

Mercer University - Science

Chief Science Officer at Dragonfly Foundation for Research and Development
Henry E.
Young, PhD
Macon, Georgia
I started studying the regeneration of tissues during limb regeneration in the adult terrestrial salamander in 1975. My thoughts were, if terrestrial salamanders can do it, why can't humans. I have spent my entire career studying this phenomenon. The bottom line answer is HUMANS CAN REGENERATE THEIR OWN DAMAGED TISSUES USING ADULT-DERIVED STEM CELLS. My research has shown that humans contain a variety of very specific precursor cells: I have isolated and/or cloned from single cells: progenitor cells, specific germ layer lineage stem cells, pluripotent stem cells, and totipotent stem cells from adult mammals, including humans. These cells individually and/or in toto have the capabilities of forming all tissues of the body, the germ cells, and the cell types within the embryonic portion of the placenta. I have also discovered that the human body knows far more about the repair process that I would hope to discover in several lifetimes. Our results have shown that the best repair we have seen in our in vivo animal studies have used the most primitive of our isolated single cell-cloned stem cells, the totipotent stem cells. My ultimate goal is to see adult-derived (totipotent and pluripotent) stem cells, either autologous or allogeneic, used to treat the various afflictions that affect human life. I am interested in the application of adult-derived (totipotent and pluripotent) stem cells for the treatment of incurable diseases and incurable traumatic injuries.

Specialties: Histochemistry, carbohydrate biochemistry, isolation of biologically active glycoproteins, proteoglycans, growth factors, hybridoma monoclonal antibodies, cell culture, CD-markers, single cell cloning, stem cell characterization, micro-array in vitro assays, flow cytometry, magnetic separation, animal surgery, wound healing, AD, ALS, CD, CIDP, COPD, IPF, MA, MD, MI, MS, OA, PD, SC, SLE, ST, TBI, TSCI, WH, nebulizations, neuropathies, intra-nasal infusions, IVs, scar inhibition, interested in incurable diseases and traumatic injuries with application of endogenous adult telomerase-positive stem cells, autologous and/or allogeneic.

Experience

    Education

    • Ohio State University - Columbus Ohio

      B.S.

      Biology
      I worked in the research laboratory of Dr. Abbott S. Gaunt as an undergraduate volunteer. Dr. Gaunt taught me anatomy and the basics of research and believed that I would one day make a significant contribution to medical research. He helped me receive a graduate student position at the University of Arkansas in Fayetteville.

    • Fairmont West HS

      HS Diploma

      College Prep

    • Case Western Reserve University

      Postdoctoral Fellow

      Carbohydrate Biochemistrry
      Worked in the research laboratory Dr. Arnold I. Caplan learning how to isolate biologically active forms of proteoglycans and glycopoteins from tissue extracellular matrices and characterize the components biochemically. My studies were performed in the connective tissues of day 11 chick embryos and NIH's aging mouse model. Besides learning carbohydrate biochemistry I also learned various aspects of cell culture and isotope radiography.

    • University of Arkansas at Fayetteville

      M.S.

      Zoology
      Master's Thesis: Limb Regeneration in the Adult Salamander, Ambystoma annulatum Cope 1889 (Amphibia: Ambystomatidae). (Dr. Claudia F. Bailey, Advisor) I learned from Dr. P.M. Johnston two phases that have forever influenced my research: "Know your model system" and "Tissue NEVER lies". Discovered environmental conditions necessary for complete limb regeneration in adult terrestrial salamanders. Described gross morphology of limb regeneration, role of nervous tissue extracellular matrices in limb regeneration, and discovered telomerase-positive stem cells in regenerating limb of the adult terrestrial salamander.

    • Texas Tech University Health Sciences Center - School of Medicine

      PhD

      Anatomy
      Texas Tech University, Lubbock, TX - Ph.D., Anatomy, 1983 Ph.D. Thesis: A Temporal Examination of Glycoconjugates During the Initiation Phase of Limb Regeneration in Adult Ambystoma. (Dr. Roger R. Markwald, Dissertation Advisor) Worked under Dr. Roger R. Markwald (mentor) to learn carbohydrate histochemistry for my dissertation studies. Wanted to identify the cells and extracellular martices that composed the regenerating limb of an adult terrestrial salamander during limb regeneration. Followed through on discovery of telomerase-positive stem cells in an adult by characterization of adult germ layer lineage stem cells and adult pluripotent stem cells during dissertation studies. learned carbohydrate histochemistry, TEM, and SEM with X-ray Microanalysis,

    Publications

    • Adult stem cells: from bench-top to bedside.

      Tissue Regeneration: Where Nanostructure Meets Biology, 3DBiotech, North Brunswick, NJ, Chap. 1, pp 1-60.

    • Adult stem cells: from bench-top to bedside.

      Tissue Regeneration: Where Nanostructure Meets Biology, 3DBiotech, North Brunswick, NJ, Chap. 1, pp 1-60.

    • Treating Parkinson disease with adult stem cells.

      J Neurological Disorders, 2:1, 2013

    • Adult stem cells: from bench-top to bedside.

      Tissue Regeneration: Where Nanostructure Meets Biology, 3DBiotech, North Brunswick, NJ, Chap. 1, pp 1-60.

    • Treating Parkinson disease with adult stem cells.

      J Neurological Disorders, 2:1, 2013

    • Pluripotent Stem Cells, Endogenous versus Reprogrammed, a Review

      MOJ Orthop Rheumatol 1(4): 00019, 2014

      There are two general categories of pluripotent stem cells, endogenous pluripotent stem cells and reprogrammed pluripotent stem cells. Endogenous pluripotent stem cells are formed during development. There are two subcategories of endogenous pluripotent stem cells, embryonic stem cells (ESCs) and postnatal (“adult”) stem cells (ASCs). Reprogrammed pluripotent stem cells are derived by either somatic cell nuclear transfer (SCNT) whereby there is the transfer of the nucleus from a differentiated cell into the cytoplasm of an enucleated oocyte or by the insertion of specific genes into terminally differentiated cells to artificially induce them to express attributes of more primitive pluripotent stem cells (induced pluripotent stem cells, iPSCs). This review outlines the developmental process and differentiative capabilities of endogenous pluripotent stem cells; the manufacture and differentiative capabilities of reprogrammed pluripotent stem cells; and the inherent characteristics of endogenous and reprogrammed pluripotent stem cells.

    • Adult stem cells: from bench-top to bedside.

      Tissue Regeneration: Where Nanostructure Meets Biology, 3DBiotech, North Brunswick, NJ, Chap. 1, pp 1-60.

    • Treating Parkinson disease with adult stem cells.

      J Neurological Disorders, 2:1, 2013

    • Pluripotent Stem Cells, Endogenous versus Reprogrammed, a Review

      MOJ Orthop Rheumatol 1(4): 00019, 2014

      There are two general categories of pluripotent stem cells, endogenous pluripotent stem cells and reprogrammed pluripotent stem cells. Endogenous pluripotent stem cells are formed during development. There are two subcategories of endogenous pluripotent stem cells, embryonic stem cells (ESCs) and postnatal (“adult”) stem cells (ASCs). Reprogrammed pluripotent stem cells are derived by either somatic cell nuclear transfer (SCNT) whereby there is the transfer of the nucleus from a differentiated cell into the cytoplasm of an enucleated oocyte or by the insertion of specific genes into terminally differentiated cells to artificially induce them to express attributes of more primitive pluripotent stem cells (induced pluripotent stem cells, iPSCs). This review outlines the developmental process and differentiative capabilities of endogenous pluripotent stem cells; the manufacture and differentiative capabilities of reprogrammed pluripotent stem cells; and the inherent characteristics of endogenous and reprogrammed pluripotent stem cells.

    online

    NEUROSCIEN

    5(1)

    • Level:
    • Credit hours: 0
    Load More