Oakland University - Biology
PhD
Evolutionary biology and Astrobiology
Genomics
Genetics
Science
Fast and Slow Implementations of Relaxed-Clock Methods Show Similar Patterns of Accuracy in Estimating Divergence Times
Sudhir Kumar
Paul Billing-Ross
Phylogenetic analyses are using increasingly larger data sets for estimating divergence times. With this increase in data sizes
the computation time required is becoming a bottleneck in evolutionary investigations. Our recent study of two relaxed-clock programs (BEAST and MultiDivTime [MDT]) showed their usefulness in time estimation; however
they place a significant computational time burden on biologists even for moderately small data sets. Here
we report speed and accuracy of another relaxed-clock program (MCMCTree
MC2T). We find it to be much faster than both MDT and BEAST while producing comparable time estimates. These results will encourage the analysis of larger data sets as well as the evaluation of the robustness of estimated times to changes in the model of evolutionary rates and clock calibrations.
Fast and Slow Implementations of Relaxed-Clock Methods Show Similar Patterns of Accuracy in Estimating Divergence Times
Fabia Ursula
Battistuzzi
Oakland University
Oakland Univeristy
Arizona State University
Arizona State University
Assistant Professor
Oakland University
Associate Professor
Oakland Univeristy