Erin E. Parker
- Courses4
- Reviews4
- School: Coastal Carolina University
- Campus:
- Department: Chemistry
- Email address: Join to see
- Phone: Join to see
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Location:
100 Chanticleer Dr E
Conway, SC - 29528 - Dates at Coastal Carolina University: January 2018 - December 2019
- Office Hours: Join to see
Biography
Coastal Carolina University - Chemistry
Experience
Education
Winthrop University
Bachelor's Degree
Chemistry
University of Notre Dame
Doctor of Philosophy (Ph.D.)
Organic Chemistry
University of Notre Dame
Laboratory Instructor/Undergraduate Mentor
Trained and guided an undergraduate student in organic chemistry principles, complex data analysis, and experimental and instrument techniques which resulted to their co-authoring of a scientific publication.University of Notre Dame
Ph.D. Organic Chemistry
Discovered and optimized novel methods for chemical synthesis, tested the viability of new reactions using model systems, and communicated those findings in regional and national conferences as well as peer-reviewed publications. Selected project experience: Led efforts in the mechanistic elucidation of propargylic alcohol formation via isolation of a sensitive, key intermediate, which provided a more coherent understanding of the chemical process and allowed for the method’s implementation in more complex systems. Developed a new method for rapidly synthesizing oxindole structures, spearheaded compound characterization, and subsequently built a library of 13 compounds, of which 4 possessed low micromolar activity against brain cancer cell lines.University of Notre Dame
Assisted in raising over $20,000 for Holy Cross mission work in Uganda. "Strong bodies gight, that weak bodies may be nourished."
Publications
An Amine-Free Approach Toward N-Toluenesulfonyl Amidine Construction: A Phosphite-Mediated Beckmann-Like Coupling of Oximes and p-Toluenesulfonyl Azide
Angewandte Chemie International Edition
An Amine-Free Approach Toward N-Toluenesulfonyl Amidine Construction: A Phosphite-Mediated Beckmann-Like Coupling of Oximes and p-Toluenesulfonyl Azide
Angewandte Chemie International Edition
Stereochemical implications in the synthesis of 3,3′-spirocyclopropyl oxindoles from β-aryl/alkyl-substituted alkylidene oxindoles
Tetrahedron
3,3′-Spirocyclopropane oxindoles were synthesized in good to excellent yield and diastereoselectivity employing a Kukhtin–Ramirez reaction between readily accessible E-alkylidene oxindoles, commercially available P(NMe2)3, and α-keto esters. The stereoselectivity in the cyclopropanation event can be traced to the starting alkylidene geometry and the propensity of the exocyclic alkene to undergo isomerization in the presence of an electron rich phosphine.
An Amine-Free Approach Toward N-Toluenesulfonyl Amidine Construction: A Phosphite-Mediated Beckmann-Like Coupling of Oximes and p-Toluenesulfonyl Azide
Angewandte Chemie International Edition
Stereochemical implications in the synthesis of 3,3′-spirocyclopropyl oxindoles from β-aryl/alkyl-substituted alkylidene oxindoles
Tetrahedron
3,3′-Spirocyclopropane oxindoles were synthesized in good to excellent yield and diastereoselectivity employing a Kukhtin–Ramirez reaction between readily accessible E-alkylidene oxindoles, commercially available P(NMe2)3, and α-keto esters. The stereoselectivity in the cyclopropanation event can be traced to the starting alkylidene geometry and the propensity of the exocyclic alkene to undergo isomerization in the presence of an electron rich phosphine.
Synthesis of Phosphine-Ligated Zinc Acetylide Dimers: Enhanced Reactivity in Carbonyl Additions
Organometallics
An Amine-Free Approach Toward N-Toluenesulfonyl Amidine Construction: A Phosphite-Mediated Beckmann-Like Coupling of Oximes and p-Toluenesulfonyl Azide
Angewandte Chemie International Edition
Stereochemical implications in the synthesis of 3,3′-spirocyclopropyl oxindoles from β-aryl/alkyl-substituted alkylidene oxindoles
Tetrahedron
3,3′-Spirocyclopropane oxindoles were synthesized in good to excellent yield and diastereoselectivity employing a Kukhtin–Ramirez reaction between readily accessible E-alkylidene oxindoles, commercially available P(NMe2)3, and α-keto esters. The stereoselectivity in the cyclopropanation event can be traced to the starting alkylidene geometry and the propensity of the exocyclic alkene to undergo isomerization in the presence of an electron rich phosphine.
Synthesis of Phosphine-Ligated Zinc Acetylide Dimers: Enhanced Reactivity in Carbonyl Additions
Organometallics
Direct Acyl Substitution of Carboxylic Acids: A Chemoselective O- to N- Acyl Migration in the Traceless Staudinger Ligation.
Chemistry - A European Journal
An Amine-Free Approach Toward N-Toluenesulfonyl Amidine Construction: A Phosphite-Mediated Beckmann-Like Coupling of Oximes and p-Toluenesulfonyl Azide
Angewandte Chemie International Edition
Stereochemical implications in the synthesis of 3,3′-spirocyclopropyl oxindoles from β-aryl/alkyl-substituted alkylidene oxindoles
Tetrahedron
3,3′-Spirocyclopropane oxindoles were synthesized in good to excellent yield and diastereoselectivity employing a Kukhtin–Ramirez reaction between readily accessible E-alkylidene oxindoles, commercially available P(NMe2)3, and α-keto esters. The stereoselectivity in the cyclopropanation event can be traced to the starting alkylidene geometry and the propensity of the exocyclic alkene to undergo isomerization in the presence of an electron rich phosphine.
Synthesis of Phosphine-Ligated Zinc Acetylide Dimers: Enhanced Reactivity in Carbonyl Additions
Organometallics
Direct Acyl Substitution of Carboxylic Acids: A Chemoselective O- to N- Acyl Migration in the Traceless Staudinger Ligation.
Chemistry - A European Journal
Phosphine-Based Redox Catalysis in the Direct Traceless Staudinger Ligation of Carboxylic Acids
Angewandte Chemie International Edition
Possible Matching Profiles
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- Erin Parker
University of Toronto - English
