Resume

• 2004

  Wilson Area High School

  PhD

  Worked in the Cassimeris Lab on the role of stathmin in normal and cancerous cell survival. Briefly

  stathmin is over-expressed in cancers

  with its expression level correlating with cancer stage progression and mutation/inactivation of a cell check point protein called p53. RNAi therapies applied to cultured cells result in apoptosis

  while non-cancerous mouse embryonic fibroblasts lacking the stathmin gene survive. Towards understanding this paradox

  I have worked on characterization of microtubule dynamics in WT and KO MEFs

  as well the use of microarray and RT-PCR studies to determine what changes occur at the transcriptome level in the mouse model and in colon cancer cells lacking p53 treated with either taxol or stathmin-siRNA.

  Pharmaceutical Chemistry in a Cell Biology Lab

  American Chemical Society\nSigma Xi\nAmerican Society for Cell Biology

  Lehigh University

  Managerial Accounting

  Business Statistics

  Business Law

  Coursera Course Certificates

  Project Management: The Basics for Success

  VV8F7XQ5TCVW

• 2003

  MS

  MS in General Science - Biochemistry focus. Studied genetic distances between two clades of Bennioides newmanii (darter fish) east and west of the Mississippi River that have been genetically isolated since the end of the Pleistocene.

  Biochemistry

  Sigma Xi

• 1992

  BS

  Chemistry

  Psychology Minor

  Alpha Gamma Delta-Kappa Chapter

  Resident Advisor

  Softball

• 648

  L. M. Mahoney

  A. T. Moore

  G. L. Feiss

  This invention relates to a topical composition for prevention and treatment of viral infections.

  Therapeutic Composition

  L. M. Mahoney

  A. T. Moore

  G. L. Feiss

• 426

  This invention relates to a topical composition for prevention and treatment of viral infections.

  Anti-Viral Therapeutic Composition

• 140

  This invention relates to a topical composition for prevention and treatment of viral infections.

  Therapeutic Composition

  Mahoney; Linda M. (Phoenixville

  PA)

  Moore; Anne T. (Hatfield

  PA)

  Feiss; Gary Lee (Telford

  PA)

• Lehigh Valley Section of the American Chemical Society

  Member of the Board of Directors

  Family Connection of Easton

  Inc.

  Relay for Life Participant and Past Team Captain

  American Cancer Society

  Analytical Chemistry

  Cell Biology

  UV/Vis

  Tissue Culture

  Molecular Biology

  Cell

  Cell Culture

  Protein Analysis

  NMR

  Chromatography

  Protein Purification

  PCR

  Mass Spectrometry

  Biochemistry

  Transfection

  Fluorescence

  Chemistry

  HPLC

  Research

  Confocal Microscopy

  Cellular Entry and Nuclear Targeting By a Highly Anionic Molecular Umbrella

  Lynne Cassimeris

  Steven Regen

  Cellular Entry and Nuclear Targeting By a Highly Anionic Molecular Umbrella

  Lynne Cassimeris

  Gene expression profiles in mouse embryo fibroblasts lacking stathmin

  a microtubule regulatory protein

  reveal changes in the expression of genes contributing to cell motility

  Lynne Cassimeris

  Stathmin Regulates Centrosomal Nucleation of Microtubules and Tubulin Dimer/Polymer Partitioning

  Stathmin Regulation of Interphase Cells: Implications for Cancer Research

  Lynne Cassimeris

  Laura Eastman

  Robert Skibbens

  A collaborative publication effort.

  Positional analyses of BRCA1-dependent expression in Saccharomyces cerevisiae

  An experienced manager of people in an academic environment as a professor leading classes

  as a postdoctoral researcher guiding undergraduate researchers

  in an industrial environment as a supervisor of a small crew

  and in volunteer roles managing a softball team and Relay For Life Team. \n\nInterfaces effectively with functional teams. For example

  in academia bridging Biology and Chemistry groups resulting in a publication. Also in an industrial environment working towards new product development using an antibody directed delivery system

  working closely with formulation scientists and directors to determine strategies and next steps. With external clients as the analytical scientist on projects at a CRO resulting in completion of project scopes

  huge gains in drug product stability

  and inclusion on a patent filing as a result of those product improvements.\n\nAn investigator that constantly finds ways to apply techniques from seemingly different projects to solving new problems.\n\nHistory of working in demanding environments with short timelines and meeting project goals. Excellent Technical Writing and Editing skills as evidenced by publications

  research development reports

  validation protocol authoring and reporting

  SOP and work instruction authoring

  and successful editing of non-English speaker research works to make them ready for peer reviewed journal submissions.

  Danielle N.

  Ringhoff

  Self-employed

  Lehigh University

  Penn State University

  Northampton Community College

  Lehigh University

  Sanofi Pasteur

  DeSales University

  Azevan Pharmaceuticals

  Inc.

  Particle Sciences

  A Lubrizol Company

  DeSales University

  Bethlehem

  Pennsylvania

  -Leader in Biologics bench work and Equipment acquisition.\n-Manager of training in all Biochemical techniques and Directing of peer-colleagues involved in Biologics work\n-Biochemical Analyses for Peptide

  Protein

  Antibody products\n-Compose and Execute Testing of Drug Product in Stability Protocols\n-Qualify & Maintain In Vitro Release Testing Franz Cell Apparatus\n-HPLC Method Development\n-Client Report Generation and Review\n-GLP Verification and cGMP Validation protocol authoring and Execution\n-Project Management\n-Generate and Deliver Reports to Clients\n-Testing of APIs and performance of Forced Degradation Studies\n-Support and Resource for other Group Members

  Biochemical Analyst

  Particle Sciences

  A Lubrizol Company

  Tannersville

  PA

  Spring 2016 Teaching of General Chemistry II Lecture.\nSummer 1 2016 Teaching of General Chemistry I Lecture & Lab.

  Adjunct Assistant Professor

  Northampton Community College

  Bethlehem

  PA

  Investigated treatments targeting low-pH disease micro-environments such as cancer and inflammatory diseases. Assisted in establishing collaborative opportunities with faculty and researchers at both Moravian College and Fox Chase Cancer Center. Instrumental in getting a brand new research laboratory up and running for a new professor

  including ordering and installing equipment. Trained new graduate students and undergraduates in the use of various instrumentation and techniques such as cell culture

  microscopy

  SDS-PAGE

  solid phase protein synthesis

  and E. coli based expression of plasmids and proteins.

  Post-Doctoral Researcher

  Lehigh University

  Bethlehem

  PA

  Summer Session II Laboratory: CHM 031-Chemistry of Solutions and Equilibria

  Visiting Assistant Professor

  Lehigh University

  Tannersville

  Pennsylvania

  Teaching both General Chemistry & Organic Chemistry Lectures & Labs.

  Assistant Professor

  Northampton Community College

  Swiftwater

  Pennsylvania

  -Leading development of HPLC-CAD & GC-MS techniques for analyses of trace lipids

  cholesterols

  and Extractable/Leachable compounds.\n-LC-MS analyses of vaccine proteins for identification using protein digestion and proteomics software.\n-Experience in Capillary Electrophoresis of vaccine proteins using SDS-CE on PA800-Plus.\n

  Contract Scientist III

  Sanofi Pasteur

  Working with Cactus Communications

  Inc. in the Center of Excellence: Biochemistry

  Genetics

  and Molecular Biology. Edits of manuscripts and academic works.

  Self-employed

  Contract Scientist

  Basic research on novel therapeutics targeted against disorders of stress

  mood

  and behavior. Primary functions include confocal microscopy with fluorescence quantification

  method development for Multiple Fluorescence labeling of tissue samples.

  Azevan Pharmaceuticals

  Inc.

  Visiting Assistant Professor

  2010 Summer Session II: CHM 031 - Chemical Equilibria in Solutions\nFall 2010: CHM/BIOS 371 - Elements of Biochemistry I; CHM 030 - Chemistry Studio Lab\nSpring 2011: CHM 030 - General Chemistry Lecture and Studio Lab

  Lehigh University

  Adjunct Chemistry Professor

  Fall 2010: CHEM 110 & CHEM 111 (General Chemistry Lecture and Lab)\nSpring 2011: CHEM 111 (General Chemistry Lab)

  Penn State University

  Adjunct Professor of Chemistry

  Teaching CH 104: Introduction to Organic and Biological Chemistry Lecture & Laboratory to Sport & Exercise Science Majors

  as well as some Nursing and Non-Science Majors.

  DeSales University

  Adjunct Professor

  Teaching CHM107 Laboratory: General

  Organic

  & Biochemistry. Targeted to Nursing Majors.

  DeSales University