Resume

• Research

  Immunology

  Molecular Biology

  Science

  Life Sciences

  Genomics

  PCR

  Microbiology

  Cell

  Microsoft Office

  Laboratory

  Genetics

  Biotechnology

  Cancer

  Western Blotting

  Cell Culture

  Biochemistry

  Cell Biology

  Goparaju

  Ph.D.

  Chandra

  Goparaju

  Ph.D.

  Bergen Community College

  NATIONAL HEALTH RESEARCH INSTITUTES

  Aurora Degree College

  Kakatiya University

  Molecular and Structural Endocrinology

  NYU Langone Medical Center

  Columbia University in the City of New York

  Molecular and Structural Endocrinology

  PHD Fellow

  Kakatiya University

  Research Associate

  •\tEstrogens action in the brain: Investigated novel molecular mechanisms of estrogen actions in the brain regions associated with various neuronal disorders such as Alzheimer’s and Parkinson’s diseases

  Ischemic Stroke and depression disorders. \n•\tInvestigated the mechanisms underlying in the synthesis of endogenous 17alpha-estradiol

  a brain derived estrogen and its regulatory action on various genes associated with brain related diseases\n•\tEpigenetics of Tumor Suppressor Genes: Investigated the epigenetic alterations such as SNP’s

  methylation and histone acetylation / deacetylation of various tumor suppressor genes associated with germ cell tumors and cervical cancers. \n•\tDesigned and analyzed gene expression

  genotyping and SNP’s.\n\n

  Columbia University in the City of New York

  NATIONAL HEALTH RESEARCH INSTITUTES

  •\tDrug Discovery & Validation for Cancers: Studied importance of PPAR family genes in cancer drug discovery. Purified and characterized recombinant proteins. Developed cell based ligand-binding assays for the need of high-through put methods for drug-targeted screening.\n•\tStudied the structural and biochemical catalytic properties of DPP IV

  a member of prolyl peptidases family as a validated and effective drug target for the treatment of type II diabetes.\n

  Post doctoral fellow

  Taiwan

  Hanamkonda

  Telagana

  India

  Aurora Degree College

  NYU Langone Medical Center

  New York

  •\tInvestigating Immune biomarker signatures for lung cancer and mesothelioma both in tissue and in the blood for discovery and validation. Conducting research to uncover novel deferentially expressed genes and pathways associated with tumor biology in particularly mesothelioma and lung cancers. \n•\tLead key-clinical translational research initiative in exploring microRNA/mRNA dysregulations

  Next Generation Sequencing

  Epigenomics and identifying novel biomarkers & drug targets for mesothelioma and lung cancers. \n•\tApplying bioinformatics and computational systems biology to basic translational medical research in cancer

  including functional genomics

  experimental design

  hypothesis generation and publication of critical findings with a focus on personalized therapies.\n•\tLeading and managing cross-functional teams of laboratory technicians engaged in large-scale projects and actively participating in large multi-site program project that integrates computer and experimental biologists at centers across the United States

  with a direct role in biomarker discovery and validation in circulating body fluids Mentored and trained laboratory technicians

  post-docs

  resident fellows and summer students.\n•\tDeveloped Multiplex SOMAmer assay for the diagnostic and prognostic cancer biomarkers.\n•\tExploring the gene expression immune-oncology profiles of circulating blood components for the early detection and diagnosis of Lung cancers and mesothelioma: \n•\tExploring circulating microRNA profiling in the blood plasma and exosomes of lung cancers and mesothelioma.\n\n\n\nhttp://www.ncbi.nlm.nih.gov/pubmed/?term=goparaju+c\n\nhttp://www.ncbi.nlm.nih.gov/pubmed/?term=goparju+c\n\nPatents:\n\n12/25/14 - 20140378336 - DIAGNOSIS OF CELL PROLIFERATIVE DISEASE\nInventors: Harvey I. Pass

  Chandra Goparaju \n\nOSTEOPONTIN ISOFORM A INHIBITORS AND METHODS OF USE\nApplication number: 20150004157\nInventors: Harvey I. Pass

  Jessica S. Donington

  Chandra M. Goparaju

  Senior Scientist

  PARAMUS

  NJ

  •\tSince 2017

  as an adjunct

  I have been teaching microbiology for undergraduate students both class room lectures and labs.

  Adjunct Professor

  Department of Biology & Horticulture

  Bergen Community College

  Doctor of Philosophy - PhD

  Environmental Toxiology

  Kakatiya University (University College of Pharmaceutical Sciences)