Resume

• 2012

  Rosemount

  •\tLicensed substitute teacher in MN; taught 6th through 12th grade math and science classes in Apple Valley

  Eagan

  Rosemount. This was a great learning experience especially on adapting to fluid situations.\n•\tAttended the Technological Leadership Institute at the University of Minnesota

  College of Science and Engineering. Completed a Master’s degree in Security Technologies

  emphasis on risk analysis and communication.\n•\tContract employment UPS\n•\tFulfilled a yearlong service on a Federal Grand Jury

  which evaluates if probable cause exists for federal charges. This experience provided new perspective on risks in our lives and increased appreciation for those who serve to protect us. \n•\tStay-at-home Dad

  coach for youth softball; a time of hard work and high reward.

  Rosemount

• 2011

  M.S.

  Coursework: Security Science & Technology

  Critical Infrastructure Protection

  Methods Theory & Applications

  Technology for Homeland Security

  Dynamic System Modeling

  Psychological Intelligence for Homeland Security

  Risk and Threat Assessment & Management

  Security Law Social Responsibility & Ethics

  Information & Cyber Security

  Communication of Risk

  Public Policy

  Science and Technology Policy

  Epidemiology.\nCapstone Project: Risk analysis of Recombinant Protein Production of Toxins

  Security Technologies

  University of Minnesota-Twin Cities

• 2008

  University of Minnesota

  Sylvan Learning Centers

  Synopsis: Characterization of a part of the immune system that may prevent the mouth from being infected by germs that can infect the stomach or lungs. Identified and characterized a new regulatory mechanism that bacteria

  like Strep.

  use to stay within sites of infection (one mechanism for how bacteria decide should I stay or should I go). \n\nResearch Projects: \tInnate Immune Response and Signaling

  Gram Positive Bacterial Adhesion and Regulation \n\nProjects involved analysis and characterization of Metalloproteins

  DNA-binding proteins

  two component systems

  and protein-protein interactions; employing structural biology

  bioinformatics

  signaling pathway characterization

  protein engineering (rational modifications)

  protein family analysis

  molecular biology (gene knockout)

  western blots and ELISAs

  and protein purification.\nLinux and Windows operating systems.\nFortunate to mentor and aid several fantastic graduate students.

  University of Minnesota

  Licensed Insurance Agent

  MN State Licensed in: Property & Casualty (Home

  Auto

  Commercial) Life & Health (Health

  Disability

  Life

  Annuities)

  Farm Bureau Financial Services

• 2000

  Indiana University School of Medicine

  Farm Bureau Financial Services

  Indianapolis

  IN

  Synopsis: The ability of a cell’s skeleton to transform to different shapes depending on the need is vital to function and development. This regulation involves a plethora of proteins as great as any other signaling system within biology

  yet remains largely uncharacterized. Additionally

  these cytoskeletal processes are targeted by intracellular pathogens. I worked on the identification and characterization of unique features and bottlenecks within this regulatory network for the identification of targets for drug discovery.\n\nResearch Projects:\tNeuronal Senescence (including Alzheimer’s disease)

  Neuronal Birth Defects

  Cancer

  and Infectious Pathogens. \n\nProjects involved analysis and characterization of microtubule-binding proteins

  antibodies

  and protein-protein interactions; employing structural biology

  bioinformatics

  protein engineering (rational modifications)

  protein family analysis and annotation

  protein overexpression

  molecular biology (cloning

  site-directed mutagenesis)

  protein purification

  crystallization

  x-ray crystallography

  protein domain analysis

  biochemical assay optimization

  synchrotron data collections at Argonne National Laboratory and Lawrence Berkeley Laboratory.\nUnix system administration

  database creation and annotation.\nMy time also included the mentoring and training of many remarkable master’s and undergraduate students. Additionally

  lectured in courses to high school

  undergraduate

  and graduate students

  as well as medical fellows.

  Research Faculty

  Indiana University School of Medicine

  University of St. Thomas

• 1995

  The University of Michigan

  Sylvan Learning Centers

  Ann Arbor

  MI

  Synopsis: I provided an atomic level functional description of the protein Methylenetetrahydrofolate Reductase. Approximately 12% of the population is homozygous for a mutation

  which increases the risk of developing cardiovascular disease in adults and neural tube birth defects in newborns. This mutation is why pregnant women take folate and grains have been supplemented. I proposed functional features on how this protein works and requires folate supplementation

  these predictions have since been confirmed.\n\nResearch Projects: \tOne Carbon metabolism

  Cardiovascular Disease in Adults and Neural Tube Birth Defects in Newborns

  cyclic GMP signaling. \n\nProjects involved analysis and characterization of redox enzymes containing Folate

  FAD and Nicotinamide cofactors; employing structural biology

  bioinformatics

  protein engineering (rational modifications)

  protein family analysis

  protein purification

  optimization of protein stability

  crystallization

  x-ray crystallography

  synchrotron data collections at Cornell High Energy Synchrotron Source.\nUnix

  Apple

  and Windows operating systems.\nInteracted with and aided an amazing group of graduate students.\nSought out and served as a lecturer for the senior level biochemistry course in Department of Chemistry during this time.

  Postdoctoral Research Fellow

  The University of Michigan

• 1989

  Dow Chemical Company

  The Rockefeller University

  Midland

  MI

  Synopsis: Biotechnology and the insertion of genes to create insect-resistant plants\n\nProject involved gene insertion in plant cells

  employing electroporation and tissue culture.

  Summer Intern

  Dow Chemical Company

  New York

  NY

  Synopsis: Solved the novel structure of the protein Delta Prime and proposed how its C shape functions as a one way inch worm at the level of molecular machinery. I identified other proteins which work in a similar fashion. These predictions were later confirmed and expanded by others to what is now known as the AAA+ superfamily

  one of the most common and oldest protein families.\n\nResearch Projects: \tDNA Replication

  Zinc Fingers

  Gene activation

  Redox Enzymes\n\nProjects involved analysis and characterization of DNA-binding proteins

  ATPases and GTPases

  protein domain motions

  and protein-protein interactions; utilizing structural biology

  bioinformatics

  protein engineering (rational modifications)

  protein family analysis

  protein purification

  crystallization

  x-ray crystallography

  protein evolution

  synchrotron data collections at Cornell High Energy Synchrotron Source and Brookhaven National Laboratory.\nUnix and Apple operating systems.\nParticipated in high school outreach during graduate school at Rockefeller University

  which has no undergraduate students

  Graduate Fellow

  The Rockefeller University

  Okemos High School

  Ph.D.

  Qualifying courses in Biochemistry

  Biophysical Chemistry

  Cell Biology

  Molecular Biology

  Molecular Evolution

  Structural Biology\nDissertation: Structural Studies on the DNA Replication Apparatus: X-Ray Crystal Structure of the Delta Prime Subunit of Escherichia coli DNA Polymerase III.\nDissertation work was published in Cell

  Molecular Biophysics

  Rockefeller University

• 1987

  The University of Michigan Medical School

  Department of Microbiology and Immunology

  University of St. Thomas

  Ann Arbor

  MI

  Synopsis: Investigated the mode of cell wall synthesis in gram negative bacteria

  the target of penicillin and other antibiotics. \n\nUtilizing radiolabeling and kinetics

  was able to disprove one model of cell wall synthesis which was favored at the time. Additionally

  I proctored for the self-paced biochemistry course while an undergraduate at the University of Michigan.

  Undergraduate Research

  The University of Michigan Medical School

  Department of Microbiology and Immunology

• 1985

  B.S.

  Honors Thesis in Molecular and Cellular Biology

  Chemistry

  Molecular and Cellular Biology

  Member of Phi Lambda Upsilon

  national honors chemistry fraternity

  The University of Michigan

• Research

  Biochemistry

  Cell Biology

  Protein Expression

  Cell Culture

  Protein Purification

  Molecular Biology

  Science

  Protein Chemistry

  Structural Biology

  Guenther