Experience

• North Carolina State University

  Graduate Research Assistant

  • Completed the complete asymmetric synthesis of two natural products, N-acetylslaframine and 1-deoxynojirimycin. The enantioselective synthesis of N-acetylslaframine was highlighted by a cyclocarbamation reaction as well as a selective palladium catalyzed reduction. The enantiospecific synthesis of the azasuger 1-deoxynojirimycin involved the enantioselective installation of four continuous stereogenic centers in a concise synthetic route. Investigated model studies toward the synthesis of castanospermine.

• Liberty University

  Professor Of Chemistry

  Alan worked at Liberty University as a Professor Of Chemistry

• Liberty University

  Associate Professor

  Alan worked at Liberty University as a Associate Professor

• RTI International

  Postdoc

  Design and synthesis of peripherally restricted CB1 antagonists for use in treating liver fibrosis. Generating ideas and text for proposals to be submitted to NIH. Co-authored four papers, and in the process of preparing an additional manuscript for publication. Moved the project out of crowded patent space into a chemo-type with less prior art. This work resulted in two patent applications having been filed.

• Johnston Community College

  Adjunct Instructor

  Teaching in the BioWork curriculum.

• Icagen

  Senior Research Scientist

  Participated in all stages of project development from proposal of new indications with specific targets to helping pick compounds for late stage preclinical studies. Generated and helped to evaluate intellectual property position resulting in co-inventor status on 4 patents and 7 additional patent applications. Designed and synthesized a compound that advanced to late stage preclinical studies. Designed and synthesized compounds to optimize a chemo-type for potency, selectivity, pharmaco kinetic profile. Supervised a lab associate and served as a chemistry liaison for one project. Presented material at company wide meetings to an audience of varied scientist.