Resume

• 2011

  Boehringer Ingelheim Pharmaceuticals

  Ridgefield CT

  Scientist IV - Medicinal Chemistry Dept. - High-Throughput Biology

  Boehringer Ingelheim Pharmaceuticals

  Groton CT 06340

  Scientist - Primary Pharmacology Group

  Pfizer

  Protein Purification and Enzymology\n•\tPurified and Characterized native and recombinant proteins using various chromatographic techniques\n•\tDesigned Cloning and Expression Constructs in support of High-Throughput Screening\n•\tDesigned and implemented screening assay for activity testing

  Bayer Pharmaceuticals

• 2003

  Scientist – Diabetes Discovery Biology\nReagent provision and acquisition in the support of multiple

  ongoing Diabetes’ Projects.\n•\tDeveloped ex-vivo assays to monitor the activity states of target proteins as a tool for measuring in vivo efficacy\n•\tIndependently implemented BacMam Technologies and Small to Medium Scale Mammalian and Insect cell Fermentation \n•\tDeveloped Ex-vivo Binding and Functional Assay for various Diabetes targets\n•\tCloned

  sub-cloned and expressed numerous biological targets to be used in both primary and secondary compound screens.\n•\tEstablished and managed CRO Contracts with our Laboratory in an effort to streamline research

  resulting in decreased timelines and increase productivity. \n•\tTrained and mentored several entry level Scientists\n\nScientist – Obesity Discovery Biology\n\tCloning and expression of various human

  mouse

  and monkey genes linked to the Obese Phenotype.\t\n•\tDeveloped an Electro-Spray MS protocol for the detection and Quantitation of Acetyl -CoA’s\n•\tAided in the development of a High-Throughput MS Plate Based Assay for Acetyl-CoA’s. Resulted in the identification of lead compound series. \n•\tSupported Program by developing and running primary HT-MS screen\n•\tGenerated Stable and Transient Cell lines expressing Human and Rodent Serotonergic Receptors as a model for in vivo pharmacology.\n•\tScreened Peptides in a GTPγS assay modeling intestinal incretin activation furthering our peptidomimetic program\n•\tThree Pfizer Individual Performance Awards: Recognizes when Employee Goes Above and Beyond in the accomplishment of Departmental Goals\n•\t2005 Pfizer Teamwork Award: Opiate Project Team\nAssociate Scientist – Inflammation Discovery Biology\n•\tCloning

  Expression and Purification of various Inflammation targets in bacterial and insect cell expression systems.

  Pfizer

  Pfizer

  Groton CT

  Senior Scientist - Primary Pharmacology Group (PPG) - Discovery Sciences

  Pfizer Pharmaceuticals

• 1993

  Schleicher and Schuell

  Bayer Pharmaceuticals

  Schleicher and Schuell

  Middlesex Community College

  CT

  Middletown

  Connecticut

  Anatomy and Physiology 1 and 2

  Adjunct Faculty

• 1990

  MS

  Molecular and Cellular Biology

• 1984

  Keene High School

• Middlesex Community College

  CT

  Pfizer

  Pfizer Pharmaceuticals